http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200124038-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e9bca1120ab9d2f65b138f53e3eda4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0272d70c9ba3abebfdf08dc6b96f1120 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a423b3896fb137308c231f90d9a6e6e0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 |
| filingDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f722fb39d133727f80924a454e63337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bf0520ad5ec242f7285fc3a29c44a49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab0511de368b8476f0694ccb18bdfcf1 |
| publicationDate | 2020-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20200124038-A |
| titleOfInvention | Pharmaceutical composition for prevention or treatment of peripheral neuropathy caused by overexpression of PMP22 comprising miR-381 as an effective ingredient |
| abstract | The present invention relates to a pharmaceutical composition for preventing or treating peripheral neuropathy caused by overexpression of PMP22, comprising microRNA-381 (miR-381) as an active ingredient. Through specific examples, the present inventors have determined that miR-381 according to the present invention effectively inhibits the expression of PMP22 in Charcoal-Marie-tus disease type 1A (CMT1A), which is a peripheral neuropathy caused by overexpression of PMP22, thereby impairing motor performance and It was confirmed that the physiological and behavioral improvement effects, such as increasing myelin formation of nerve cells, were confirmed. According to the present invention, miR-381 can be usefully used as a preventive or therapeutic use of peripheral neuropathy caused by overexpression of PMP22. It is expected. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023070086-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023136624-A1 |
| priorityDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 325.