abstract |
The present invention provides a compound with interferon gene stimulating factor (STING) agonistic bioactivity that can be used in the treatment of tumors in patients suffering from tumors. Compounds are compounds of formula (I) as defined herein: . Compounds for the practice of the methods of the present invention can be delivered via oral delivery for systemic exposure, as well as intratumoral delivery. Anti-tumor therapy using the compound of formula (I) may further comprise administration of an effective dose of an immune-checkpoint targeting drug. |