| abstract |
The present invention relates to a pharmaceutical composition for preventing or treating liver cancer comprising an inhibitor of expression of let-7i-5p as an active ingredient, wherein the inhibitor of expression of let-7i-5p according to the present invention includes tumor cell growth in hepatocellular carcinoma, Since it has inhibited proliferation, migration and invasion, microtubule formation, and angiogenesis activity, it can be used as a pharmaceutical composition for preventing and treating liver cancer, and providing information for diagnosis or prognosis of liver cancer according to its expression control and liver cancer It can be used for screening methods for candidate therapeutic substances. |