| abstract |
The present invention provides a method for preparing a substituted pyrazole compound of formula II, which can be used as an intermediate for the preparation of a substituted piperidine urea compound useful in the treatment of dilated cardiomyopathy (DCM). R 2 is independently selected from F, C1-C4 alkyl, C1-C4 haloalkyl, R 3 is independently selected from H, F, C1-C4 alkyl, C1-C4 haloalkyl, and R 4 is C1-C4 Alkyl, R 6 is H or a protecting group, and R 7 is selected from H, Cl or trialkylsilyl. |