| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e7566f00a7dc09b35e4868c20ad2307 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2527-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-04 |
| filingDate |
2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9174bef542ca5ba634b57444cd408b63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_019d63c0be965ba921f910f94fa2c6dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82f003926f3804b3c36af58359f7c992 |
| publicationDate |
2020-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20200113832-A |
| titleOfInvention |
A method for regulation of gene expression in stem cell by using mechanical stiffness of hydrogel |
| abstract |
The present invention relates to a method for regulating gene expression of stem cells using the mechanical strength of a hydrogel, and specifically, gene expression of stem cells comprising the step of encapsulating the stem cells inside a three-dimensional polymer cell scaffold in which the mechanical strength is controlled. It is about how to adjust. The method for regulating gene expression of stem cells using the mechanical strength of the hydrogel according to the present invention is a simple and safe method of controlling the mechanical strength of the hydrogel without using genetic manipulation or viral vectors, etc. The pattern can be adjusted, and further, by reprogramming the metabolic processes of stem cells, the next generation of highly efficient stem cells can be mass-produced. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023036922-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4147730-A1 |
| priorityDate |
2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |