abstract |
The present invention is a derivative of the following formula (I) (Wherein, rings A, X, Y, Z, R A , R 1 , R 2 , R 3 and R 4 are as described in the specification), their preparation, their pharmaceutically acceptable salts, and pharmaceuticals To their use as, pharmaceutical compositions containing at least one compound of formula (I), and in particular to their use as C5a receptor modulators. |