abstract |
The present invention relates to an age tracking method using body fluids. More specifically, the present invention relates to a method for tracking the age of a test subject by measuring the degree of DNA methylation for a specific CpG site of a target gene in a body fluid derived from a test subject, most preferably a saliva sample. will be. In the field of forensic science and forensic medicine, tracking the age of a victim or perpetrator from evidence can be a great clue to case resolution. Until now, the most effective biomarker for age estimation is known as a DNA methylation marker, but the conventional age estimation method has a problem that it takes a lot of time and cost to track age because a number of genes must be analyzed. The present invention relates to an age tracking method using a bodily fluid derived from a test object, most preferably a saliva sample. The age of the test subject can be accurately tracked by methylation of the CpG positions of four target genes, and the analysis method is simple. It is expected to be widely used in the field of forensic science and forensic medicine, as the cost and cost are reduced. |