| abstract |
The present invention is an inhibitor of factor XII (FXII) for use in treating or preventing chronic kidney disease, renal fibrosis, glomerulosclerosis, kidney wounds, ischemia/reperfusion injury and/or acute kidney injury in original or transplanted kidney, chronic kidney disease , Renal fibrosis, glomerulosclerosis, renal wounds, ischemia/reperfusion injury in the original or transplanted kidney, acute kidney injury, renal fibrosis as a result of renal transplantation/allograft rejection, and/or renal transplantation as a result of rejection or recurrent underlying disease Kits comprising one inhibitor of factor XII, for use in treating or preventing fibrosis of allografts, and chronic kidney disease, renal fibrosis, glomerulosclerosis, renal wounds, ischemic/reperfusion injury and/or in the original or transplanted kidney It relates to an anti-factor XII (FXII) antibody or antigen binding fragment thereof comprising one inhibitor of factor XII for use in treating or preventing acute kidney injury. |