| abstract |
The present invention relates to a monoclonal antibody, or antigen-binding fragment thereof, that specifically binds to the EGF2 domain of human colon cancer secreted protein-2 (CCSP-2). The monoclonal antibody of the present invention, or antigen-binding fragment thereof, specifically binds to the EGF2 domain of CCSP-2, thereby significantly improving affinity compared to a peptide specifically binding to existing CCSP-2, and The specificity was further improved compared to the antibody against CCSP-2. Accordingly, CCSP-2 can be specifically detected at the protein level in the future to enable accurate diagnosis. |