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filingDate 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2b873b072b8899745bde6ecd53bd609
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publicationDate 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20200092955-A
titleOfInvention New catecholamine prodrug for use in the treatment of Parkinson's disease
abstract The present invention provides compounds of formula I, which are prodrugs of catecholamines for use in the treatment of neurodegenerative diseases and disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention, and methods of treating neurodegenerative or neuropsychiatric diseases and disorders, particularly Parkinson's disease, using the compounds of the invention. Accordingly, the present invention relates to a compound of formula (Id) or a pharmaceutically acceptable salt thereof, wherein R 1 is H and R 2 is selected from one of the following substituents (i) and (ii); R1 is selected from one of the following substituents (i) and (ii), and R2 is H; R1 and R2 are both represented by the following substituent (i); R1 and R2 are both represented by the following substituents (ii); R1 is substituent (i) and R2 is substituent (ii); R1 is substituent (ii) and R2 is substituent (i); Here, * represents an attachment point; The carbon atom at the point of attachment on substituent (i) is the S-configuration. [Formula Id] [Formula i] [Formula ii]
priorityDate 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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