abstract |
Compounds of Formula I, Formula Ia and Formula Ib, disclosed herein together with analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof It is described in. [Formula I] [Formula Ia] [Formula Ib] This compound inhibits PRMT5 and is useful as a therapeutic agent or emollient for diseases related to cell growth, such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease, and the like. |