abstract |
The present invention provides a substituted pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compound of formula (I), a method for preparing the compound, pharmaceutical compositions and combinations comprising the compound, and alone or other activity Use of these compounds in combination with ingredients to prepare pharmaceutical compositions for the treatment or prevention of diseases, in particular neurogenic diseases, includes: Where R 1 , R 2 and R 3 are as defined herein. |