| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2276405ae0e23cfcd15651de21c8565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e9bca1120ab9d2f65b138f53e3eda4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e7575b6eae054378e85b08269ed0df3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eb1eaca5aa8d56ece28f1805176bc22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4266735e46f6048b3131e67f6dbd7e81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e000b64f8c2257823a9bc25c6e095b1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2fdc8d35f8219bae191f3fabf0d9cde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_681543a41a913550064f8d6004814bfc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_908989de5013c54018ab732c9bb6a8a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1044db89f46ac7a416ec9c88b04ef35e |
| publicationDate |
2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20200077436-A |
| titleOfInvention |
Fusion Protein Comprising Human Lefty A Protein Variants And Use Thereof |
| abstract |
The present invention relates to a human Lefty A protein variant having improved productivity and stability, a fusion protein comprising the protein variant, and a composition for preventing and/or treating neuromuscular disease comprising the protein variant or fusion protein. The present invention improves the expression level and production yield in animal cells based on superior stability than the naturally occurring human Lefty A protein by producing a human Lefty A protein variant and a fusion protein containing the variant. In addition, the administration of the produced Human Lefty A protein variant or fusion protein can restore the neurological function and motor function of the neurological disease model animal. It can be effectively prevented or treated. |
| priorityDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |