| abstract |
The present invention relates to a functional cosmetic composition for improving skin wrinkles using the extract by preparing an extract containing a high content of flavonoids from chrysanthemum petals, and more specifically, inducing the proliferation of human dermal cells, and MAPKs signal pathway proteins P38, EKR , Natural substance-based functionality that can be used as a composition of wrinkle improvement functional cosmetics with excellent wrinkle improvement effect by inhibiting MMP-1, one of collagen degrading enzymes, at the transcription and protein expression stage of genes through signal regulation to suppress phosphorylation of JNK It relates to the invention of the composition. |