| abstract |
The present invention relates to a composition for the prevention, improvement or treatment of atopic dermatitis, which contains the Gosseng hydrolyzate as an active ingredient, and the enzyme hydrolyzate of the Gosseng leaf extract, which is the active ingredient of the present invention, inhibits the production of NO and atopic related factors. It has the effect of suppressing the secretion of (IL-4 and INF-γ). In addition, the enzyme hydrolyzate of the extract of the gossip leaf of the present invention is superior to the ethanol extract of the gossip leaf or the acid hydrolyzate of the extract of the gossip leaf, and has an excellent effect of improving skin lesions of the animal model caused by atopic dermatitis, skin thickness, and blood IL-4. , Since it has the effect of significantly reducing the concentration of IgE and CCL17, the composition containing the enzyme hydrolyzate of the gossip extract of the present invention as an active ingredient is a quasi-drug for atopic dermatitis, a health functional food for patients with atopic dermatitis, a material for the treatment of atopic dermatitis It can be useful. |