| abstract |
The present invention discloses a composition for improving lung diseases such as inflammation and chronic obstructive pulmonary disease using Pediococcus pentosaceus . Pediococcus pentosaceus significantly reduces the number of inflammatory cells, such as neutrophils and macrophages, as major etiologies in lung lavage fluid in COPD animal models, and IL-6, IL in lung lavage fluid and lung tissue -1β, IL-17, TNF-α, IFN-γ, GM-CSF, MIP-2, KC, TARC, MCP-1, MDC, etc., by inhibiting the expression of inflammatory cytokines and chemokines, has respiratory disease improving activity . |