| abstract |
In the present invention, a wild type respiratory syncytial virus (RSV) fusion protein (F protein) membrane transmembrane (transmembrane) domain of the fusion protein (F protein) is deleted, the C-terminal polymerized domain derived from a foreign protein linked, respiratory cells It provides a recombinant fusion protein (F protein) of fusion virus (RSV). The recombinant fusion protein of the present invention is soluble and can maintain the trimer of F protein. The recombinant fusion protein of the present invention, and the vaccine composition comprising the same, can be expected to have excellent immunity-inducing effect. |