http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200049489-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff283c7d6797987f01db547f606e6b32 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0356 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afeed37cf78db69298f961d122e545ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cbf0b70790574150597f09d83aedd18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_349074add4b82a5ef91e08e5465b40d3 |
| publicationDate | 2020-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20200049489-A |
| titleOfInvention | Method for producing animal model having young adulthood depression |
| abstract | The present invention comprises the steps of: 1) inducing prenatal stress to a mouse fetus by applying a continuous and unpredictable stress to the mother in the prenatal phase; 2) inducing maternal separation stress in infancy of the mouse induced stress before the birth of 1); And 3) inducing social defeat stress by exposing the mouse in which the parental separation stress of 2) is induced to adult mice in adolescence. The adolescent depression mouse model of the present invention manufactured by continuous exposure to mild stress during a period shows major symptoms of depression, such as anxiety, lethargy and loss of pleasure, and recovers the main symptoms when administered with antidepressants, thereby analyzing the cause and pathology of adolescent depression , It can be useful as a mouse model for depression in adolescence for the development of a treatment for depression. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102214214-B1 |
| priorityDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 492.