| abstract |
The present invention relates to a method for generating in vitro cultured hepatocytes using an endoplasmic reticulum stress reliever and an in vitro cultured hepatocyte generated therefrom, specifically, to differentiate from a predifferentiated stem cell to hepatocytes using a vesicle stress reliever, or to culture a liver cancer cell line, or , It is a technology for preparing in vitro cultured hepatocytes that can be used for predicting hepatotoxicity of new drug candidates by culturing primary cultured hepatocytes. |