| abstract |
Adenovirus comprising the sequence of formula (I): 5'ITR-B 1 -B A -B 2 -B X -B B -B Y -B 3 -3'ITR (I), where B Y is It contains a transgene cassette containing four transgenes, and the gene encodes FAP-BITE, CXL10, CXL9 and IFN. The present disclosure also extends to pharmaceutical compositions comprising viruses, and the use of the virus or formulation is therapeutic. |