| abstract |
The present invention synthesizes N- (3 ', 6'-dihydroxy-3-oxospyro [isoindoline-1,9'-xanthene] -2-yl) -2-hydroxybenzamide, and reprecipitates it A method for detecting zinc (Zn 2+ ) ions using a fluorescent organic nanoparticle obtained through a method is provided. The novel fluorescein derivative compound of the present invention, a method for manufacturing the same, and a method for detecting zinc ions using the same show a very low detection limit (0.0011 µg / ml) in aqueous solution for zinc ions, and are non-toxic and detect zinc ions in living cells It can be used in biomedical and environmental fields. |