Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0272d70c9ba3abebfdf08dc6b96f1120 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab3413f8184feb74be59b7ed962a5b97 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate |
2018-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36d6ea34b5f93d8b540022724961892d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dc7ef514a0accb5c32db7a8e9df6cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bfb1ff0019c6c1ff4986af060054934 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dae916c9a18acc5fa49578ced759d45f |
publicationDate |
2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20200037523-A |
titleOfInvention |
Pharmaceutical Composition for Preventing or Treating of Fibrosis Comprising Hyaluronic acid Nanoparticles |
abstract |
The present invention relates to a pharmaceutical composition for the prevention or treatment of fibrosis containing hyaluronic acid nanoparticles. Hyaluronic acid nanoparticles formed by combining hyaluronic acid and 5β-cholanic acid or polycaprolactone according to the present invention reduce collagen deposition and α-SMA content in fibrosis model mice and inhibit mRNA expression of genes related to fibrosis symptoms. , It is useful as a composition for the prevention or treatment of fibrosis disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023287230-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220065529-A |
priorityDate |
2018-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |