| abstract |
The present invention includes prostaglandin FP receptor agonist (PFPRA) compounds and fatty acid esters (e.g. isopropyl myristate), optionally ointment bases such as hydrocarbon bases (e.g. petroleum jelly) and / or organic alcohols (e.g., Propylene glycol), and upon topical application to the skin, discloses a composition and method for its preparation, which delivers a PFPRA compound topically to a subcutaneous fat under the skin in a therapeutically effective amount. The therapeutic effect is, for example, the loss of subcutaneous fat under the skin. In addition, the present invention provides a method of reducing body fat in an individual comprising the step of topically administering the composition to the individual. |