| abstract |
The present invention relates to a composition for the prevention, improvement or treatment of arthritis comprising an extract of eccentric mushrooms, thistle extract or a mixture thereof as an active ingredient, and more specifically, Mmp3, Mmp13 or Cox2 increased by IL-1β in chondrocytes Prevention or improvement of pharmaceutical composition and / or arthritis for the prevention or treatment of arthritis, comprising as an active ingredient an extract of eccentric mushrooms, thistle extract or a mixture thereof, which has an effect of inhibiting joint inflammation or cartilage destruction by reducing the mRNA or protein expression of It provides a health functional food composition. |