Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca28a3e455e54b164e302c55168f4bb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050fc7b82c5d17d9aeb63a7cdcc546b3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-332 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-704 |
filingDate |
2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d39dee44efb6637d003f20eabdde49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc1f94d5408039ba437f6b1ef3cb6264 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fb1959ff0ddd2e98422f5074c6ec423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9cb3a0c01d5b9a0d3f0d3902deabd63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c4fd7655699773e6d1d7701157f6b3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdff0ae213aff6fa2da06b8ce38e3438 |
publicationDate |
2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20200023161-A |
titleOfInvention |
Avicularin, the pancreatic lipase inhibitor from natural resources |
abstract |
The present invention relates to a natural new material abiculin (Avicularin, quercetin-3- O -α-L-arabinofuranoside) having a pancreatic lipase inhibitory ability extracted from the Korean native medicinal plant, Polygonum aviculare L. . According to the present invention, a safe natural material-based abiculin was discovered through the identification of an effective ingredient for pancreatic lipase inhibition in natural bark grass, and can be used as a pancreatic lipacetic inhibition-based dietary supplement. In addition, the abiculin discovered in the present invention acts as a mixed form inhibitor having a strong non-competitive nature causing some reversible changes in the pancreatic lysate, disappearance of the inhibitory effect (competitive inhibitor) or ratio of the pancreatic lysate with increasing substrate concentration. Reverse denaturation (inhibition of irreversible) does not occur. Through this, the present invention provides an effective and safe natural product based pancreatic lipase inhibitor unlike the prior art. |
priorityDate |
2018-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |