| abstract |
The present invention relates to a composition for enhancing radiation sensitivity comprising NONO expression or an activity inhibitor as an active ingredient, according to the present invention, the expression level of the NONO gene or protein is specifically increased in various cancers, such as breast cancer, liver cancer, lung cancer This indicates a high correlation with the survival rate, anticancer reactivity and radiation sensitivity of cancer patients, and expression or activity inhibitors targeting NONO can be usefully used as a novel cancer therapy to suppress tumors and enhance anticancer agent reactivity and radiation sensitivity. Can be. |