| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee496f20bb0f8d60f234cb4671fafe64 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R1-645 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 |
| filingDate |
2019-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b78808321e72f35c98d2b1cf75e7481
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07b7a4ea5919ce6defb2bbe3994cf009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22b2228db4d7b1b64f982d27c913db2f |
| publicationDate |
2020-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20200021893-A |
| titleOfInvention |
Composition for growth inhibition of colorectal cancer stem cells comprising extracts of novel endolichenic fungi derived from Cetraria sp. lichen |
| abstract |
The present invention relates to a composition for inhibiting colorectal cancer stem cell growth comprising a novel extract of lichen endothelial fungus as an active ingredient, and a novel lichen endogenous fungus EL001672 (KACC 83021BP) extract isolated from Setraria lichens. Inhibits expression of colorectal cancer stem cell markers ALDH-1, CD133, CD44, Lgr-5 and Msi-1, induces the death of colorectal cancer stem cells, autologous regeneration of colorectal cancer stem cells and differentiation into cancer cells Since it shows the effect of inhibiting the tumor stem cells can be usefully used as an active ingredient of the composition for inhibiting growth. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220036113-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220120836-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200021894-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220008525-A |
| priorityDate |
2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |