abstract |
A composition is provided comprising at least 95% by weight of taxane, or a pharmaceutically acceptable salt thereof, wherein the particles have an average bulk density between about 0.050 g / cm 3 and about 0.15 g / cm 3 and / or at least 18 It has a specific surface area (SSA) of m 2 / g, 20 m 2 / g, 25 m 2 / g, 30 m 2 / g, 32 m 2 / g, 34 m 2 / g, or 35 m 2 / g. Also provided are methods of making and using such compositions. |