| abstract |
An object of the present invention is to provide an α, β unsaturated amide compound having a anticancer activity or the like, or a pharmaceutically acceptable salt thereof. Α, β unsaturated amide compounds represented by the following formula (I) or pharmaceutically acceptable salts thereof and the like have anticancer activity and the like: [Wherein, A represents a heterocyclic diyl which may have a substituent, R 1 represents a hydrogen atom or lower alkyl which may have a substituent, and R 2 may have an aryl or substituent which may have a substituent; Cycloalkyl, an aliphatic heterocyclic group which may have a substituent or an aromatic heterocyclic group which may have a substituent, represents X, -O-, -S-, -SO 2- , -NR X1- (wherein, R X1 Represents a hydrogen atom or lower alkyl), -CHR X2- (wherein R X2 represents a hydrogen atom or hydroxy), -CH = CH-, -CO- or -NH-CO-, n1 and n2 are the same or different and represent 0 or 1, respectively. |