| abstract |
The present invention provides a composition for promoting angiogenesis, a composition for treating wounds, a composition for treating stomatitis, and a composition for treating enteritis, including a hydrothermal extract of cocoon. The compositions not only increase the expression of HIF-1α and HIF-2α, but also increase the expression of VEGF capable of regenerating blood vessels essential for wound regeneration, thereby providing an excellent therapeutic effect against wounds, stomatitis and enteritis. In addition, it is excellent in affinity and safety with biological tissues, and compared to other known drugs AKB-4924, the manufacturing process is simple and can be efficiently obtained. |