Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ad4c9403364a2277dc906d5bc5642e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-77 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-18 |
filingDate |
2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23150885c06d9413cd7b825c3c54572a |
publicationDate |
2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20200017321-A |
titleOfInvention |
Method for crystallization of IsPETase protein and IsPETase variants |
abstract |
The invention Is PETase protein crystal production method, a method of screening method for screening Is PETase protein activity modulators using a three-dimensional structure of the protein and Is PETase variants, and PETase activity is increased Is PETase variants and PET decomposition using the same of It is about a method. In the present invention, a method for effectively preparing protein crystals of Is PETase was identified, and crystals obtained therefrom were obtained. In addition, by identifying the tertiary structure of Is PETase from the crystals, a variant with increased PETase activity was prepared based on this structure. The Is PETase variant can be effectively utilized in the field of PET degradation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102298651-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220123831-A |
priorityDate |
2018-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |