abstract |
The present invention provides peptides that bind to tissue factor pathway inhibitors (TFPIs), including TFPI-inhibiting peptides, and compositions thereof. Peptide complexes are also provided. The peptides inhibit TFPI, enhance thrombin formation in coagulation factor-deficient individuals, increase thrombus formation in individuals, treat blood coagulation disorders in individuals, purify TFPI, and identify TFPI-binding compounds Can be used for |