http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200004744-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050fc7b82c5d17d9aeb63a7cdcc546b3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-28 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51acf4319b86574324c6cec7d7640a8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_193f7530dff0b133204e1a279dcebdbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60420a8b44bd3023a888a767b4c71097 |
| publicationDate | 2020-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20200004744-A |
| titleOfInvention | Composition comprising OCT4 for inducing direct conversion into bone-related cells |
| abstract | The present invention is directed to treating somatic cells with at least one OCT4 expression promoting factor and musculoskeletal growth factor of an OCT4 (OCTamer-binding transcription factor 4) protein or a fusion thereof, a nucleic acid molecule encoding the protein, and a vector into which the nucleic acid molecule is introduced. Provided is a method of direct cross-differentiation from somatic cells to bone-related cells, the bone-related cells obtained therefrom, a cell therapy using the same, a screening method for therapeutic substances, and a diagnostic composition. The present invention also provides an OCT4 protein or a fusion thereof, a nucleic acid molecule encoding the protein, and a composition for preventing or treating bone-related diseases comprising at least one OCT4 expression promoting factor in a vector into which the nucleic acid molecule is introduced, or It provides a method for preventing or treating the same. The present invention also provides an OCT4 protein fusion fused to a cell-permeable delivery material or an OCT4 protein fusion fused to a cell-permeable delivery material, to which a bone tissue specific delivery material is bound. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230056851-A |
| priorityDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 635.