| abstract |
[(3-hydroxypyridine-2-carbonyl) amino] -alkanoic acid, derivatives, inter alia 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl] amino} acetic acid Also disclosed are prodrugs of [(3-hydroxypyridine-2-carbonyl) -amino] acetic acid, for example [(3-hydroxypyridine-2-carbonyl] amino}. A process for preparing acetic acid esters and {[3-hydroxypyridine-2-carbonyl] amino} acetic acid amides is disclosed, wherein the disclosed compounds are required as prolyl hydroxylase inhibitors or require prolyl hydroxylase inhibition. It is useful for the treatment of diseases. |