| abstract |
The present invention relates to an RNA interference-inducing nucleic acid in which some sequences of a specific microRNA are modified to suppress a noncanonical target gene of the microRNA. When the RNA interference-inducing nucleic acid according to the present invention is used, the microRNA may be irregular. Efficiently increase the biological function of the target gene by inhibiting the target gene, or selectively exhibit only a part of the function of the existing microRNA, that is, the biological function of the non-canonical target gene. Through the cell cycle, differentiation, dedifferentiation, morphology, migration, division, proliferation or death control is possible, it is expected to be utilized in various fields such as drugs and cosmetics. |