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filingDate 2018-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190134202-A
titleOfInvention MLPA probe for detection of sepsis-causing Gram-negative pathogens and uses thereof
abstract The present invention provides a probe for detecting sepsis-induced Gram-negative bacteria; A composition comprising the same; The kit and a method for multiple detection of major Gram-negative bacteria in sepsis patients blood using the kit. The Gram-negative bacteria detection probe, composition, kit and main gram-negative bacteria detection method according to the present invention is optimized by hybridization time to shorten the detection time than the conventional detection time, by pre-amplifying the specific sequence of Gram-negative bacteria By increasing the sensitivity of the cells, the presence, type and drug resistance of Gram-negative bacteria can be quickly and accurately determined even in cell-free DNA samples taken from the blood of patients without nonspecific reaction with the host genomic DNA.
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