| abstract |
The present invention relates to the use of enfumafungin derivative triterpenoid antifungal compounds in combination with other antifungal agents such as azoles, polyenes, lipopeptides, and allylamides for the treatment of fungal diseases. More particularly, the present invention relates to other antifungal agents, including but not limited to voriconazole, isabuconazole, posaconazole, itraconazole and amphotericin B, for treating and / or preventing infection caused by fungi, An antifungal combination of enfumafungin derivative triterpenoids, which are inhibitors of (1,3) -β-D-glucan synthesis, for example in combination with fungal activators having activity against fungi. |