http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190129703-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d0fc2b70675ee19bd5fc464f5ae9061 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-4833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02 |
filingDate | 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06f07cdf37f4cc7f70803882c16e9df7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5ee68ff5db59974a42188a53949210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecbb832716d2484e60d8890f1f7bf72f |
publicationDate | 2019-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20190129703-A |
titleOfInvention | Screening system for inhibitors of astrocyte-specific passive conductance and its application |
abstract | The present invention relates to a composition capable of regulating astrocyte specific passive conductivity, and further relates to a system for screening a glial specific passive conductivity inhibitor using the drug, and the use thereof. By using the spagine (Spadin) passive conduction inhibitory effect of the spade according to the present invention, it can be used as a passive conduction inhibitor search system, using astrocytes that inhibit the gene expression of TREK-1 or TWIK-1 ion channel Therefore, it is possible to develop a screening system for the discovery of substances that control TWIK-1 / TREK-1 heterozygous-dependent and non-dependent passive conduction, and to contribute to the study of related physiological phenomena, pathogenesis of diseases and the development of therapies. . |
priorityDate | 2018-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.