| abstract |
The present invention relates to a composition for the prevention or treatment of bone diseases comprising gentiana lutea extract as an active ingredient, in one embodiment of the present invention, the gentiana lutea extract osteoclasts of mononuclear cells isolated from mouse hematopoietic stem cells Inhibit the differentiation of the furnace, and the osteoarthritis cell model has been shown to suppress the expression of osteoarthritis-inducing factors, it is possible to effectively prevent, improve, or treat osteoporosis because it can inhibit the bone absorption that destroys bones among various bone diseases In addition, since osteoarthritis-inducing factors can be suppressed, osteoarthritis can be effectively prevented, improved or treated. |