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filingDate 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190124902-A
titleOfInvention Composition for immunostaining of cleared huge biological tissue and immunostaining method for cleared huge tissue
abstract Disclosed are a composition for immunostaining of cleared giant tissue and a method for immunostaining of cleared giant biological tissue using the same. The transparent tissue for immunostaining composition is transparent in biological tissues, especially in large biological tissues having a thickness of 3 mm or more, the antibody permeability is enhanced by penetrating the antibody deep into the thick tissues to penetrate the antibody which is an immunostaining problem of conventional methods Overcoming limitations and shortening the time required for immunostaining of large tissues, it is possible to simply and quickly obtain high resolution three-dimensional bio-imaging of large biological tissues, and to identify and treat the causes of various diseases through structured images It can be useful for the development and the prediction of the effects and toxicity of drugs. Also. It can be used in combination with various medical devices, in particular, it can be useful as an in vitro diagnostic device by making a kit.
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