http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190121499-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_050fc7b82c5d17d9aeb63a7cdcc546b3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2018-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42129f7cf50ab7a3538d2ed03742ba59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5901a58d0eae0d58669acf31a6e19d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85aa921eba6b295be22a9dc3bfe3bf06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd2785b68615d9d1fe2d50f725ecf391 |
| publicationDate | 2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20190121499-A |
| titleOfInvention | Novel Patient-derived Xenograft Model of Glioblastoma and Use thereof |
| abstract | The present invention relates to a novel glioblastoma-derived xenograft model and its preparation and use, and more particularly to a glioblastoma patient-derived xenograft model that enables a rapid treatment option selection in treating glioblastomas with a short average survival. And a method for screening the patient-specific glioblastoma treatment using the same and a method thereof. A patient-derived xenograft animal model of glioblastoma according to the present invention inherently retains the characteristics of a tumor. In addition, even patients with glioblastoma cells that do not form intracranial tumors by orthotopic transplantation form tumors within 4 weeks, considering the preparation period of patient-derived cells. Treatment options can be selected within a much shorter six weeks. In addition, the patient-derived xenograft animal model of glioblastoma according to the present invention is an effective alternative by simulating the microenvironment of the brain, unlike the glioblastoma model transplanted subcutaneously. In addition, it can be easily monitored using the naked eye or simple indirect ophthalmoscope, without any additional equipment, and requires relatively small number of glioblastoma cells for the production of glioblastoma models, allowing simultaneous evaluation of multiple treatment options. useful. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220114774-A |
| priorityDate | 2018-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.