http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190119495-A

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filingDate 2018-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c60d9f49232078557ee80a3e9c0d07f1
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publicationDate 2019-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190119495-A
titleOfInvention Extracting method of liquid biopsy-derived biomaterial using homobifunctional imidoester
abstract The present invention relates to a method for extracting a liquid biopsy-derived biological material using a homo-functional imido ester group, and extracting a liquid biopsy-derived biological material using a homo-functional imidoester compound (DMA, DMP, DMS or DTBP) according to the present invention. The method can be quickly extracted without the use of special equipment, such as cell free DNA, circulating tumor DNA or exosomes, which are biomaterials present in liquid biopsies, can be used as a field diagnostic method, extracted from a smaller amount of sample than conventional methods This allows for high efficiency, time and cost savings, and ease of use. In addition, unlike the conventional extraction method using a lysis buffer, it is possible to increase the sensitivity of the detection by reducing the contamination from various cell lysates and debris resulting from cell lysis without using a lysis buffer. Biomaterials can be usefully used for the diagnosis and treatment of diseases.
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