http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190118865-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f7943e1a1abf9c1fe0154d63f82fbd0
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
filingDate 2018-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1955972cc481b78db161aa304d42bbe4
publicationDate 2019-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190118865-A
titleOfInvention Micro-structure skin absorption promoter, skin-applyable insulin containing micro-structure skin absorption promoters, and insulin administering method using skin-applyable insulin containing micro-structure skin absorption promoters
abstract The present invention relates to a skin absorption promoter of a microstructure, and more particularly, to a skin absorption promoter of a microstructure to make micro-sized holes in the skin, and to have a gap 210 open on the surface of the skin. And a groove 220 formed in the vertical direction between the blades 210. In addition, the present invention relates to insulin applied to the skin including the skin absorption promoter of the microstructure, and more specifically, to the insulin applied to the skin, the insulin component 100 and the micro-sized micropores are formed on the skin. It is characterized by another configuration that includes a skin absorption promoter 200, thereby serving to promote the insulin component 100 is absorbed through the skin. In addition, the present invention relates to a method for administering insulin using insulin applied to the skin including the skin absorption promoter of the microstructure, and more specifically, to a method for administering insulin using insulin applied to the skin, the method comprising: (1) a microstructure Applying the insulin (10) containing the skin absorption promoter of the use site; (2) at the site applied in the step (1), the skin absorption promoter 200 of the microstructure is embedded in the skin to form micropores; And (3) absorbing the insulin component 100 through the skin through the micropores formed in the step (2). According to the insulin applied to the skin including the skin absorption promoter of the microstructure proposed in the present invention and the insulin administration method using the same, the gap is formed in the skin by the wings formed on the skin absorption promoter of the microstructure, and the gap is formed into the gap. By allowing the insulin component to be injected into the skin along the 'V' shaped groove, the insulin component, which is a polymer that is typically impossible to deliver through the skin, can be injected through the skin. In addition, according to the present invention, by administering the insulin to the patient by applying to the skin, it is possible to inject the insulin safely and conveniently by improving the disadvantages such as the pain of the conventional infusion method. In addition, according to the present invention, by allowing insulin to be administered through a large area of the skin, only a part of the drug is delivered in terms of bioavailability and burden of surrounding tissue due to the high concentration of conventional insulin local delivery. The shortcomings, such as, are improved so that an appropriate concentration of insulin can be administered through the skin with high bioavailability.
priorityDate 2018-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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