http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190116872-A

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filingDate 2018-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20190116872-A
titleOfInvention Biological tissue clearing kit for imaging 3-dimensional fluorescence photograph and the method of biological tissue clearing using thereof
abstract The present invention relates to a transparent kit of a biological tissue for three-dimensional fluorescence imaging and a method of using the same, the transparent kit according to the present invention is a variety of living body, such as brain, liver, lung, kidney, intestine, heart, muscle, blood vessels, etc. Immunostaining of tissues increases the penetration of antibodies without damaging the tissues, resulting in higher quality three-dimensional fluorescence images than conventional tissue clearing compositions. Bubble formation, discoloration, and black deposits do not occur. Since the transparency of biological tissues is improved and staining is possible through antibodies and staining samples in the transparent tissues, the structural images of the biological tissues can be observed in more detail, which can be useful for analyzing tissue changes that are difficult to observe. .
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