| abstract |
The present invention relates to a composition for preventing, treating or improving psoriasis comprising LGI3 and / or LGI3-derived peptide as an active ingredient, wherein the composition of the present invention promotes normal differentiation of keratinocytes to form a healthy stratum corneum of the skin. By allowing the mechanical protection function to be performed smoothly, it is possible to prevent, treat, and improve psoriasis, a hyperproliferative inflammatory skin disease, without the side effects of existing psoriasis treatments. Accordingly, the composition of the present invention is expected to be used in various aspects, such as for the treatment of psoriasis, medicinal, quasi-drug, cosmetics, cosmetic ingredients. |