| abstract |
To provide a method for detecting prognostic risk of renal cell carcinoma, which is simple and has very high sensitivity and specificity, methylrome analysis is performed on normal renal tissue, non-cancerous tissue from renal cell carcinoma and renal cell carcinoma. Done. As a result, DNA methylation at at least one CpG site of the FAM150A, GRM6, ZNF540, ZFP42, ZNF154, RIMS4, PCDHAC1, KHDRBS2, ASCL2, KCNQ1, PRAC, WNT3A, TRH, FAM78A, ZNF671, SLC13A5 and NKZ6-2 genes. It was discovered that the risk of poor prognosis of renal cell carcinoma can be detected by detecting. |