| abstract |
The present invention provides a hydrogel platform based on hyaluronic acid (HA) conjugated with a pyrogallol moiety. HA-PG conjugates of the present invention can be rapidly crosslinked by two different methods using oxidants or pH adjustment. The hydrogel of the present invention can efficiently control physical properties such as crosslinking speed, elasticity, and adhesive force according to each crosslinking method with excellent biocompatibility. The hydrogel of the present invention may be used in various fields including biopharmaceutical materials such as drug delivery, wound healing or anti-adhesion agents, medical care, and cosmetics based on such excellent stability and functionality. |