| abstract |
The present invention relates to a cargo-substituted decomposable nanobiomaterial for treating atherosclerosis, wherein the cyclodextrin or cyclodextrin derivative of the present invention, and a complex of statin-based compounds decompose cholesterol crystals by substituting cholesterol and statins from cholesterol crystals, It is absorbed into macrophages and foam cells to induce apoptosis, thereby inhibiting atherosclerosis and regressing atherosclerotic plaques, and thus can be useful for the prevention or treatment of atherosclerosis. |