| abstract |
It relates to a 2,4,5-substituted pyrimidine derivative, a preparation method thereof and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. Since the compound exhibits high inhibitory ability against EGFR (epidermal growth factor receptor) wild type or mutation, it can be usefully used for the treatment of cancer expressing EGFR wild type or EGFR mutation, and particularly excellent lung cancer cell line proliferation inhibiting ability, in particular, lung cancer It can be usefully used for the treatment of. |