| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3584903efe1babebbd056e855a2cc2b3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-625
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 |
| filingDate |
2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc8069d0bf86a96b05318cfc670a940f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05450adc90a9cae0205943eefd4e1037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48db4feeeeb4afe69b7c99a73c56c3e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d46b339b93bfabb114a5941a0ed82097
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d83290362d5365063dd869fd8f1518f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37636d7079e31e91bf09f5224ad46350 |
| publicationDate |
2019-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20190086908-A |
| titleOfInvention |
Method of producing recombinant protein by combining multimerization moiety and solubility controlling technique and use thereof |
| abstract |
The present invention relates to a recombinant protein production method and a use thereof by grafting a multiplexing element and a solubility control technology, and more particularly, to a recombinant protein production method comprising a domain capable of forming a complex through a disulfide bond, The present invention relates to a method for producing a recombinant fusion protein having an improved solubility and folding ability by grafting with an inner or outer part of a target protein and expressing the fusion protein and the use thereof for pharmaceutical production or industrial production, And using recombinant control peptide to produce recombinant protein not only can overcome limitations on water solubility and folding that existing fusion partners have but also has excellent stability in the body and is widely used for industrial applications including protein drugs It is expected to be possible. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109022389-A |
| priorityDate |
2018-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |